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Juxtaparanode region of axon

WebbA form of familial myoclonic epilepsy, a neurologic disorder characterized by cortical hand tremors, myoclonic jerks and occasional generalized or focal seizures with a non-progressive or very slowly progressive disease course. Webb24 dec. 2024 · Assembly and Function of the Juxtaparanodal Kv1 Complex in Health and Disease. The precise axonal distribution of specific potassium channels is known to …

29738 - Gene ResultKcnab2 potassium voltage-gated channel subfamily …

Webb开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebbThe continual wrapping of the Schwann cell myelin membrane (my) forms a multilamellar layer that is electron dense. A longitudinal section of the paranodal region of a … blackest matte black vehicle wrap https://mariancare.org

UniProt

WebbDescription: Homo sapiens contactin associated protein-like 2 (CNTNAP2), mRNA. RefSeq Summary (NM_014141): This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and … WebbFunction. Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits ( PubMed: 7499366, PubMed: 7603988, PubMed: 17156368, PubMed: 17540341, PubMed: 19713757 ). Modulates action potentials via its effect on the pore-forming alpha subunits ( By similarity ). WebbIn the juxtaparanodes of a large myelinated PNS axon, the axon and the Schwann cell form a complex structural relation, the axon-Schwann cell network, which is composed … blackest nba player

29738 - Gene ResultKcnab2 potassium voltage-gated channel subfamily …

Category:Human Gene CNTNAP2 (uc003weu.2)

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Juxtaparanode region of axon

UniProt

Webb30 sep. 2024 · This study aims to evaluate the molecular differences of the nodes of Ranvier and the initial axon segment (AIS) and juxtaparanode region (JXP) as the potential cause of phenotypic variation of CIDP while also seeking new pathomechanisms since JXP is sequestered behind the paranode and autoantibodies may not access the … WebbLocated in cytosol; juxtaparanode region of axon; and pinceau fiber. Is extrinsic component of cytoplasmic side of plasma membrane. Part of potassium channel complex. Colocalizes with microtubule. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2). [provided by Alliance of Genome …

Juxtaparanode region of axon

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Webb28 aug. 2024 · Processes behind magnetization transfer (MT) in a biological system (neurons). (a) Image of a cortical neuron (Cuntz et al. 2010) on the left; it has a disproportional amount of surface area associated with myelin sheaths (orange; 48 m 2) and dendrite (blue; 1631 m 2).(b) Microenvironment surrounding a dendritic spine … Webb使用AUCell识别单细胞rna数据中具有活性“基因集”(i.e. gene signatures)的细胞。AUCell使用“曲线下面积”(Area Under the Curve,AUC)来计算输入基因集的一个关键子集是否在每个细胞的表达基因中富集。AUC分数在所有细胞的分布允许探索signatures的相对表达。 AUCell允许在单细胞rna数据中识别具有活性基因集(如 ...

WebbCoding Region Position: hg38 chr19:38,879,155-38,893,819 Size: 14,665 ... GO:0033270 paranode region of axon GO:0042995 cell projection GO:0043204 ... GO:0043219 lateral loop GO:0043220 Schmidt-Lanterman incisure GO:0044224 juxtaparanode region of axon GO:0048471 perinuclear region of cytoplasm GO:0072686 mitotic spindle … http://amigo.geneontology.org/amigo/term/GO:0044224

WebbPredicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in immature eye; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Webb13 okt. 2024 · Located in juxtaparanode region of axon and lamellipodium. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Is active in calyx of Held. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 32.

Webbaxonal membrane into distinct molecular,structural and functional domains. These domains include the nodes of Ranvier, the paranodal junction, the juxta-paranodes and the internodal region 8,9 (FIGS 1b and 2). We will focus on the molecular mechanisms that underlie the generation and maintenance of these unique axonal domains,which are ...

http://www.informatics.jax.org/vocab/gene_ontology/GO:0044224 blackest monkey in the worldWebb13 dec. 1999 · The juxtaparanode was easily distinguished from the paranodal and nodal regions, since its diameter was conspicuously larger. Potassium channel antibody … gamefaqs armored coregamefaqs assassin\u0027s creed 2WebbSaltatory conduction in myelinated fibres depends on the specific molecular organization of highly specialized axonal domains at the node of Ranvier, the paranodal and the … blackest nba playersWebbThe protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. blackest name possibleWebbThis review summarises recent evidence supporting the involvement of the specialised nodal and perinodal domains (the paranode and juxtaparanode) of myelinated axons … gamefaqs assassin\u0027s creedWebb8 jan. 2024 · in myelinated axons 4.1B contributes to the stabilization of membrane proteins at paranodes, to the clustering of juxtaparanodal proteins, and to the regulation … blackest nfl team