Improve-it trial summary

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August undefined, 2024

WitrynaSeveral large, randomized, controlled trials have documented that cholesterol-lowering therapy with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) reduces the risk of death... http://cardiologytrials.org/detail/107/

IMPROVE-IT TRIAL - CardiologyTrials.org

Witryna18 gru 2014 · The IMPROVE-IT trial provides the first evidence from a large-scale event-driven randomized clinical trial that additional lipid modifying therapy further lowering LDL-C provides further CVD event reduction beyond statin … WitrynaOther trials have shown that digital adherence technologies (SMS-based and those based on medication event reminder monitors), implemented in real-time, can improve successful treatment outcomes. It is important, though, to understand the cost of delivering such interventions and also how these can be implemented in routine practice. campbell river to buttle lake

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Witryna10 lis 2024 · These considerations led to the design of the Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT). 15 Icosapent ethyl is a … Witryna1 lis 2008 · The IMPROVE-IT trial has become even more important since the release of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial results, 24 which compared the effects the combination of ezetimibe and high-dose simvastatin with high-dose simvastatin alone on carotid … Witryna1 maj 2016 · Recent findings: IMPROVE-IT is the first trial that demonstrates a significant clinical benefit of a nonstatin hypolipidemic agent (ezetimibe) used in combination with statin (simvastatin)... campbell river to little river ferry

IMPROVE-IT, un punto de inflexión en el tratamiento hipolipemiante ...

[The IMPROVE-IT trial] - PubMed

WitrynaThe IMPROVE trial was more ‘real world’ but has been criticised for including participants who did not have a ruptured aneurysm or who died before repair could be accomplished. This serves to highlight the … Witryna12 kwi 2015 · The IMPROVE-IT trial, launched 9 years ago, has finally provided physicians with long-term efficacy and safety evidence for ezetimibe. The large-scale … first state diva fund factsheetWitryna12 lut 2024 · IMPROVE-IT, a contemporary, large, and well-designed trial, unequivocally demonstrated reduction in CV outcomes with ezetimibe when added to statin therapy. The benefits are seen in both sexes, elderly, CKD, diabetes mellitus, and in patients with prior CABG. It also reduces biomarkers and induces plaque regression like statins. first state dinner at trump white house

"Witryna20 wrz 2005 · Brief Summary: This is a randomized, active-control, double-blind study of subjects with stabilized high-risk acute coronary syndrome (ACS). The primary … " - Improve-it trial summary

Improve-it trial summary

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WitrynaRationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of … WitrynaVytorin Efficacy International Trial (IMPROVE-IT) evaluated the effect of ezetimibe combined with simvastatin, as compared with that of simva-statin alone, in stable …

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Witryna19 lis 2014 · IMPROVE IT posiblemente inducirá algún cambio en las guías en futuras revisiones. Otra posibilidad es que pueda ayudar a evitar la posibilidad de … WitrynaFindings In a prespecified analysis of 15 281 patients enrolled in IMPROVE-IT, patients achieving an LDL-C level of less than 30 mg/dL at 1 month after acute coronary …

WitrynaRecent findings: IMPROVE-IT is the first trial that demonstrates a significant clinical benefit of a nonstatin hypolipidemic agent (ezetimibe) used in combination with statin … WitrynaIn order to improve compliance on the posting of results, the primary aim of this communication is to remind all sponsors about their obligation for the reporting of clinical trial summaries in the EU Clinical Trials Database. In the spirit of the EU legislation, it is important that all stakeholders act

WitrynaOther trials have shown that digital adherence technologies (SMS-based and those based on medication event reminder monitors), implemented in real-time, can … Witryna1 cze 2024 · PINNACLE Cohort and IMPROVE-IT Trial Patient Characteristics View LargeDownload 1. Cannon CP, Blazing MA, Giugliano RP, Ezetimibe added to statin therapy after acute coronary syndromes. N Engl J Med. 2015;372(25):2387-2397. PubMedGoogle ScholarCrossref 2. Maddox TM, Masoudi FA, Oetgen

Witryna1 wrz 2024 · This trial is registered at ClinicalTrials.gov, NCT00125593, and ISRCTN54137607. 4650 patients were assigned to receive simvastatin plus ezetimibe and 4620 to placebo.

Witryna10 cze 2014 · It is predicted, therefore, the trial will complete in 2014. IMPROVE-IT when reported will be the largest and longest contemporary trial focusing specifically on … first state dividend advantage 2012 factsheetWitrynaThe Pravastatin or Atorvastatin Evaluation and Infection Therapy trial (PROVE-IT/TIMI-22) showed that in patients with acute coronary syndromes, aggressive lipid-lowering using atorvastatin 80 mg/day provided greater protection against death or major cardiovascular events than did moderate lipid-low … Lessons from the PROVE-IT trial. first state dividend advantage fund factsheetWitrynaSummary The Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) was a large double-blind, randomised controlled trial to investigate … first state dispensary menuWitrynaIMPROVE-IT TRIAL; Problem: Recent acute coronary syndrome with raised LDL: Format: Double-blind RCT: Treatment: Ezetimibe 10mg + Simvastatin 40mg: Control: … campbell river to sayward distanceWitrynaplacebo‐controlled trial design, the benefit could have been due to the statin alone. SHARP What IMPROVE‐IT may add? Ezetimibe may modestly lower CV event risk … campbell river tree serviceWitryna23 lis 2024 · When to write a summary. Step 1: Read the text. Step 2: Break the text down into sections. Step 3: Identify the key points in each section. Step 4: Write the summary. Step 5: Check the summary against the article. Frequently asked questions about summarizing. first state dividend advantage factsheetWitryna3 lut 2024 · Lay Summary Non-Hispanic Black Americans experience the highest, and most rapidly increasing, rates of obesity and diseases attributed at least in part to poor diet quality. In contrast to restrictive diets, which can be ineffective and often harmful, there is a well-established connection between home cooking and lower body mass … campbell river used boats craigslist