WebFeb 3, 2024 · Understanding how endogenous chaperones modulate tau misfolding could guide future therapies. Here, we show that the immunophilin FKBP12, the 12-kDa FK506-binding protein (also known as FKBP prolyl isomerase 1A), regulates the neuronal resilience by chaperoning a specific structure in monomeric tau. WebFK506 binding proteins (FKBPs) are a family of highly conserved proteins in eukaryotes. The prototype of this protein family, FKBP12, is the binding partner for immunosuppressive drugs FK506 and rapamycin. FKBP12 functions as a cis/trans peptidyl prolyl isomerase (PPIase) that catalyzes interconversion between prolyl cis/trans conformations.
FKBP1AP1 FKBP prolyl isomerase 1A pseudogene 1
WebJan 4, 2024 · FKBP-type peptidyl-prolyl cis-trans isomerase (NbFKPPIase) plays a role in the replication of begomoviruses in Nicotiana benthamiana. Expression of the gene encoding NbFKPPIase was examined by reverse transcription quantitative PCR, and expression of the genes encoding coat proteins of begomoviruses was examined by … WebMar 10, 2024 · Protein domains: FKBP_C (FKBP-type peptidyl-prolyl cis–trans isomerase), EFh (EF-Hand), TPR (Tetratricopeptide repeats). The EvolView was used to map the phylogenetic tree and the structural ... literary criticism literary lenses
FKBP1A Gene - GeneCards FKB1A Protein FKB1A Antibody
WebFKBP1A, FKBP prolyl isomerase 1A Vertebrate Orthologs 5 Human Diseases more Diseases 1 with Fkbp1a mouse models Mutations, Alleles, and Phenotypes less Phenotype Summary 43 phenotypes from 4 alleles in 9 genetic backgrounds 24 phenotypes from multigenic genotypes 88 phenotype references Phenotype Overview Phenotype Overview Web李东伦 苏 松 甘元涛 赵少勇 郑英俊 淦 宇 方 程 李 波 (1 西南医科大学附属医院肝胆外科,四川省泸州市 646000,电子邮箱:[email protected];2 四川省乐山市人民医院肝胆外科,乐山市 614000;3 四川省宜宾市第二人民医院肝胆外科,宜宾市 644000) Web丁香通为您提供重组人TOP1商品详情介绍:价格:¥800,货号:ENZ-306,CAS号:无,品牌:ProSpec,产地:以色列,详见丁香通重组人TOP1商品详情页; importance of postsecondary education