WebJul 19, 2024 · CircRHOT1 is overexpressed in HCC tissues. To identify essential circRNAs expressed in HCC tissues, we analyzed online-available datasets concerning the circRNA profiles in HCC tissues (GSE94508 and GSE97332) [7, 20].We found that many circRNAs are overexpressed in HCC tissues compared to peritumor tissues (Fig. 1a). Among them, … WebMCs were stimulated by the hepatitis C virus E2 envelope glycoprotein (HCV-E2), which increased exosomal miRNA-490 levels that affected HCC cells, thereby inhibiting the EGFR/AKT/ERK1/2 pathway, and ultimately ... Su et al. revealed that circRNA Cdr1as derived from HCC cells was mainly located in exosomes and directly bound to miR-1270, …
The care cascade for hepatitis C virus and prognosis of chronic ...
WebHepatocellular carcinoma (HCC) is a type of malignant tumor. miRNAs are noncoding RNAs and their differential expression patterns are observed in HCC-induced by alcoholism, HBV and HCV infections. By acting as a competing endogenous RNA (ceRNA), circRNA regulates the miRNA function, indirectly controlling the gene expression and leading to … WebApr 11, 2024 · It is known that HCC can occur after SVR in the liver of advanced fibrosis (F3). Therefore, early diagnosis and treatment of chronic hepatitis C through a surveillance program is important. Recently, one studied published hepatitis C virus care cascade in one Korea tertiary institution . However, except this study, few studies have analyzed the ... simulation method of teaching
Frontiers Accentuating CircRNA-miRNA-Transcription Factors …
WebFeb 17, 2024 · Increasing evidence shows that change in circRNA expression has an extensive effect on the biological behavior of HCC. In this study, we comprehensively … WebApr 20, 2024 · In fact, some artificial circRNAs have been engineered and showed their therapeutic potential in treating HCV infection and gastric cancer. In this review, we introduce the potential of circRNAs as biomarkers for HCC diagnosis and prognosis, as therapeutic targets for HCC treatments and discuss the challenges in circRNA research … WebThe mechanism by which HCV dysregulates expression of cellular circRNA and a possible role of circPSD3 and the other circRNAs in HCV-induced HCC remain to be explored. ... Role of Virus-Induced ... rcw anallergenic wet